Main page > Method > Publications > Effects of enhanced human chemosensitivity on ventilatory responses to exercise
Effects of enhanced human chemosensitivity on ventilatory responses to exercise
It is not clear what the effects of different types of intermittent hypoxia have on human exercise ventilation. The purpose of this study was to determine whether short-duration intermittent hypoxia, and the subsequent augmentation of the hypoxic ventilatory response (HVR), would lead to an increase in ventilatory responses during exercise at sea level. It was hypothesized that subjects exposed to short-duration intermittent hypoxia would have a greater increase in the ventilatory response to exercise compared to those exposed to long-duration intermittent hypoxia. Subjects (n=17, male) were randomly assigned to short-duration intermittent hypoxia (SDIH: 5 min of 12% O2separated by 5 min of normoxia for 1 h) or long-duration intermittent hypoxia (LDIH: 30 min of 12% O2). Both groups had 10 exposures over a 12 day period. The HVR was measured on days 1 and 12.
Foster GE, McKenzie DC, Sheel AW
Source: Exp Physiol